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Coadministration of hypothalamic PKC- inhibitor rottlerin with OAG prevented the ability of OAG to activate PKC- and lower glucose production. 下丘腦蛋白激酶C抑制劑卡馬拉素和OAG同時給葯會抑制OAG活化蛋白激酶C的能力竝降低葡萄糖的生成。