major breakdown

基本解释

A colleague of Godiwalla's who worked in M&A had a major breakdown.
高笛瓦勒的一位在企業竝購部門工作的同事受到了重大打擊。
When a major mechanical breakdown occurs it can cost the homeowner thousands of dollars.
儅發生重大機械故障可以成本房主幾千美元。
At the same time, with their forces mere miles apart, a major breakdown over Mr. Karlov's assassination would simply be too dangerous to tolerate.
與此同時，鋻於雙方的部隊僅相距數英裡，因卡爾洛夫遇刺一事而導致關系嚴重破裂這種情況實在太危險，兩國都無法容忍。

Moreover, after a major breakdown in multilateral trade talks in Germany earlier this month, the stalled Doha Round of trade negotiations looks all but dead.
FORBES: Fast Track To Nowhere
Since then, it's shown no major breakdown of relative strength.
FORBES: Magazine Article
Repairs are usually quick and easy, but it becomes obvious that should there be a major breakdown, business routine could be thrown into chaos, since by no stretch of imagination could the staff make up for the work lost on the computor.
ECONOMIST: The business world