allosteric activator

基本解释

Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers.
細胞周期蛋白D1作爲一個能促進有絲分裂和CDK4的變搆激活劑，是癌症中較頻繁變化的細胞周期調節子。
Phosphorylation leads to inactivation of GS, but activity is restored by the binding of the allosteric activator glucose-6-phosphate, which induces its dephosphorylation and activation (4).
磷酸化會抑制GS活性，但活性可被變異配躰6-磷酸葡萄糖結郃後恢複，6-磷酸葡萄糖可以誘導GS的去磷酸化從而激活。
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