be down and out

基本解释

Now that you have a basic idea of what needs to be done, sit down and plan out your strategy.
现在，您有一个需要做什么基本的想法，坐下来计划你的战略。
One battalion is out, the Marines are out to the extent that we said they were going to come out, and then four more are coming down and be out by July, just like he recommended.
一个营是，海军陆战队员是在某种程度上我们说他们打算出来，并且四更然后下来和是在7月前，如他推荐了。
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"There are so many things you can't anticipate when you create a new technology, " he says. "Who would have predicted that the Internet would be taking down shopping malls and wiping out newspapers?
“在发明一个新科技时，有太多的事情你无法预计”他说：“谁会预测到互联网将击败商场、消灭报纸？
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Witnesses say at one point early Friday morning, The chief mediator at the talks, former Mozambican President Joaquim Chissano ordered Mr.Rajoelina to sit down and be quiet when he threatened to walk out.
These signaling proteins play important roles in determining how many cells differentiate down particular pathways and they turn out also to be very useful for treating diseases of those pathways.
这些信号蛋白在决定特定分化路径上,有多少细胞在分化时起着重要作用,且在治疗疾病方面也很有用,同样也是利用这些机制
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but the fact is they are intelligent, ambitious,motivated and to be just a pawn in the story of a whole bunch of men fighting it out,rolling around and getting down-and-dirty, while there you are just a vision in a tight cat-suit is just a boring thing."

She might even learn a thing or two about what it means to be down and out.
FORBES: Taxing Mr. and Mrs. Jones